Cosmelan MD
& Melasma Treatments in
La   Jolla, CA

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Clinically Proven Treatments for Pigmentation and Melasma

At PRFCT in La Jolla, we specialize in treating complex pigment conditions like melasma, sun damage, and hormonal discoloration. Our Cosmelan MD protocol is physician-curated and clinically guided to improve visible pigmentation while protecting your skin barrier. Trusted by patients across San Diego for treating melasma safely and effectively.

What Is Melasma?

Melasma is a chronic pigment condition that causes gray-brown patches on the face, often triggered by sun exposure, hormonal changes, or genetics. It commonly appears on the cheeks, forehead, upper lip, and jawline. Unlike superficial discoloration, melasma is notoriously difficult to treat without professional guidance and prescription-strength solutions.

What Are Cosmelan MD & Melanostop Treatments?

At HelloPRFCT, we offer two powerful solutions:

Cosmelan MD Peel

A prescription-strength chemical depigmentation peel that targets stubborn melanin buildup in the skin. This treatment includes a powerful in-office application followed by a guided at-home protocol.

Melanostop System

A multi-layered microneedling treatment using tranexamic acid and a blend of brightening agents to address pigment formation at multiple levels of the skin.

Pricing

Cosmelan® MD Peel

$950

Real Results, Real Skin 

View before & after transformations from our melasma protocols. See improvement in tone, clarity, and long-term pigment suppression.

Treatment: cosmelan MD
38 days
Provider: Dr. Zoe

Treatment: cosmelan MD
45 days
Provider: Dr. Zoe

Treatment: cosmelan MD
32 days
Provider: Dr. Zoe

Treatment: cosmelan MD

21 days

Provider: Dr. Zoe

Treatment: cosmelan MD

Day 13 of 90 days

Provider: Dr. Zoe

Treatment: cosmelan MD

90 days

Provider: Dr. Zoe

Treatment: cosmelan MD

90 days

Provider: Dr. Zoe

Treatment: cosmelan MD

90 days

Provider: Dr. Zoe

What to Expect: The PRFCT Pigment Protocol

1

Clinical Skin Consultation

We evaluate your pigmentation type, severity, skin tone, and sensitivities to determine the best protocol.

2

Pre-Treatment Prep

You may be advised to precondition your skin with pigment suppressors or retinoids prior to your treatment.

3

In-Clinic Procedure

For Cosmelan:
A powerful peel is applied in-office and left on for several hours before being rinsed off at home.
For Melanostop:
The skin is numbed, a peel is applied, and the depigmentation serum is microneedled into the dermis.

4

Guided 
Aftercare

Post-treatment instructions and a take-home skincare regimen are included for optimal results and safe recovery.

5

Series & Maintenance

Melanostop is best done in a series of 3 spaced 2–4 weeks apart. Cosmelan may be repeated as advised by your provider.

Skin Conditions Treated

  • Hormonal Melasma (pregnancy, menopause, birth control)
  • Sun-induced hyperpigmentation
  • Acne-related dark spots
  • Post-inflammatory discoloration
  • Uneven tone and skin dullness
  • Pigment-prone ethnic skin types (Fitzpatrick III–VI)

Pre & Post Care Instructions

Before Your Appointment

  • Avoid lasers, chemical peels, microneedling, waxing, or excessive sun exposure in the weeks leading up to treatment.
  • Discontinue retinol, glycolic acid, and hydroquinone products as directed prior to starting Cosmelan MD.
  • Inform your provider if you are pregnant, nursing, prone to cold sores, rosacea, or recently received Botox, filler, or a COVID vaccine.

After Your Treatment

  • Follow the full 3-month home care protocol exactly as directed, including Cosmelan 2, Melan Recovery Cream, and daily SPF use.
  • Avoid sun exposure, heat, sweating, swimming, makeup, and additional skin treatments during the initial recovery period.
  • Do not use retinols, acids, hydroquinone, or other active products unless specifically instructed by your provider.

What Our Clients Say

PRFCT is top-tier. The environment is elegant and calming, and the team is warm, professional, and I felt immediately at ease there. My treatment plan was personalized, and the results have been amazing—my skin feels smoother, firmer, and more radiant!!

— Carolina P

I had a great experience at PRFCT from the moment I called to book an appointment. The front desk was super friendly and helpful!I saw Lexi for a consultation, and she was absolutely amazing. She took the time to thoroughly assess my concerns and walked me through my options in...

I had a great experience at PRFCT from the moment I called to book an appointment. The front desk was super friendly and helpful!
I saw Lexi for a consultation, and she was absolutely amazing. She took the time to thoroughly assess my concerns and walked me through my options in such a knowledgeable and approachable way. I never felt rushed or pressured. I ended up receiving a ThermoClear treatment, a lip flip, and a melasma treatment, along with a personalized skincare regimen—using mostly products I already own, which I really appreciated! Lexi’s expertise and attention to detail made all the difference in my overall care.
I am now 3 weeks out and have already seen a noticeable different in my skin. Can’t recommend PRFCT and Lexie enough. I’ll definitely be back.

— Claire G.

Lexi has saved my skin and helped me feel like myself again so many times over the years! Her expertise guidance and warm demeanor is something I really look forward too. She has my absolute trust and full recommendation. Thank you for always keeping it real Lex!

— Patti Y

Ready to Treat Your Melasma With Confidence?

Schedule a consultation at HelloPRFCT in La Jolla to find out which treatment is right for you. Whether you're just beginning your pigment journey or have tried everything else, our curated solutions are designed to finally get you results.

Frequently Asked Questions

Yes, when applied by trained professionals, Cosmelan is safe and effective for all Fitzpatrick types, including darker skin.